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Reduction of DNMT3a and RORA in the nucleus accumbens plays a causal role in post-traumatic stress disorder-like behavior: reversal by combinatorial epigenetic therapy.
Warhaftig, Gal; Zifman, Noa; Sokolik, Chaya Mushka; Massart, Renaud; Gabay, Orshay; Sapozhnikov, Daniel; Vaisheva, Farida; Lictenstein, Yehuda; Confortti, Noa; Ahdoot, Hadas; Jacob, Avi; Bareli, Tzofnat; Szyf, Moshe; Yadid, Gal.
Afiliação
  • Warhaftig G; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
  • Zifman N; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
  • Sokolik CM; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
  • Massart R; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada.
  • Gabay O; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
  • Sapozhnikov D; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada.
  • Vaisheva F; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada.
  • Lictenstein Y; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
  • Confortti N; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
  • Ahdoot H; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
  • Jacob A; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
  • Bareli T; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
  • Szyf M; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada. moshe.szyf@mcgill.ca.
  • Yadid G; Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, QC, Canada. moshe.szyf@mcgill.ca.
Mol Psychiatry ; 26(12): 7481-7497, 2021 12.
Article em En | MEDLINE | ID: mdl-34253866
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Transtornos de Estresse Pós-Traumáticos / Membro 1 do Grupo F da Subfamília 1 de Receptores Nucleares / DNA Metiltransferase 3A Limite: Animals Idioma: En Revista: Mol Psychiatry Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Transtornos de Estresse Pós-Traumáticos / Membro 1 do Grupo F da Subfamília 1 de Receptores Nucleares / DNA Metiltransferase 3A Limite: Animals Idioma: En Revista: Mol Psychiatry Ano de publicação: 2021 Tipo de documento: Article