Protective Effects of Estrogen on Cardiovascular Disease Mediated by Oxidative Stress.
Oxid Med Cell Longev
; 2021: 5523516, 2021.
Article
em En
| MEDLINE
| ID: mdl-34257804
ABSTRACT
Perimenopause is an important stage of female senescence. Epidemiological investigation has shown that the incidence of cardiovascular disease in premenopausal women is lower than that in men, and the incidence of cardiovascular disease in postmenopausal women is significantly higher than that in men. This phenomenon reveals that estrogen has a definite protective effect on the cardiovascular system. In the cardiovascular system, oxidative stress is considered important in the pathogenesis of atherosclerosis, myocardial dysfunction, cardiac hypertrophy, heart failure, and myocardial ischemia. From the perspective of oxidative stress, estrogen plays a regulatory role in the cardiovascular system through the estrogen receptor, providing strategies for the treatment of menopausal women with cardiovascular diseases.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Cardiovasculares
/
Estresse Oxidativo
/
Estrogênios
Limite:
Female
/
Humans
Idioma:
En
Revista:
Oxid Med Cell Longev
Ano de publicação:
2021
Tipo de documento:
Article