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Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneity through mitochondrial oxidative stress.
Sharma, Pratibha; Xu, Jihong; Williams, Katie; Easley, Michelle; Elder, J Brad; Lonser, Russell; Lang, Frederick F; Lapalombella, Rosa; Sampath, Deepa; Puduvalli, Vinay K.
Afiliação
  • Sharma P; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Xu J; Division of Neurooncology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Williams K; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Easley M; Division of Hematology Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Elder JB; Department of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Lonser R; Department of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Lang FF; Department of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Lapalombella R; Division of Hematology Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Sampath D; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Puduvalli VK; Division of Hematology Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Neuro Oncol ; 24(2): 229-244, 2022 02 01.
Article em En | MEDLINE | ID: mdl-34260721
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glioma / NAD Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Neuro Oncol Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glioma / NAD Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Neuro Oncol Ano de publicação: 2022 Tipo de documento: Article