Cigarette smoke extract combined with LPS down-regulates the expression of MRP2 in chronic pulmonary inflammation may be related to FXR.

Fang, Xin; Zhang, Shuyi; Wang, Zihao; Zhou, Jian; Qi, Chuanzong; Song, Jue

Fang, Xin; Zhang, Shuyi; Wang, Zihao; Zhou, Jian; Qi, Chuanzong; Song, Jue.

Afiliação

Fang X; Institute for Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, China; Institute for the Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China.
Zhang S; Institute for Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, China; Institute for the Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China.
Wang Z; Institute for Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, China; Institute for the Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China.
Zhou J; Institute for Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, China; Institute for the Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China.
Qi C; Institute for Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, China; Institute for the Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China.
Song J; Institute for Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, China; Institute for the Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, China. Electronic addre

Mol Immunol ; 137: 174-186, 2021 09.

Article em En | MEDLINE | ID: mdl-34273652

Assuntos

Regulação para Baixo/efeitos dos fármacos; Lipopolissacarídeos/farmacologia; Proteínas Associadas à Resistência a Múltiplos Medicamentos/metabolismo; Pneumonia/metabolismo; Receptores Citoplasmáticos e Nucleares/metabolismo; Produtos do Tabaco/efeitos adversos; Células A549; Animais; Linhagem Celular Tumoral; Fumar Cigarros/efeitos adversos; Humanos; Mediadores da Inflamação/metabolismo; Pulmão/efeitos dos fármacos; Pulmão/metabolismo; Proteína 2 Associada à Farmacorresistência Múltipla; NF-kappa B/metabolismo; Doença Pulmonar Obstrutiva Crônica/metabolismo; Ratos; Ratos Sprague-Dawley; Transdução de Sinais/efeitos dos fármacos; Fumaça/efeitos adversos; Regulação para Cima/efeitos dos fármacos

Palavras-chave

Chronic pulmonary inflammation; Cigarette smoke extract; FXR; MRP2

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 4_TD Base de dados: MEDLINE Assunto principal: Pneumonia / Regulação para Baixo / Lipopolissacarídeos / Receptores Citoplasmáticos e Nucleares / Proteínas Associadas à Resistência a Múltiplos Medicamentos / Produtos do Tabaco Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Immunol Ano de publicação: 2021 Tipo de documento: Article

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