Cycloartane-type triterpenoids from the whole plants of Macrosolen bidoupensis.
J Asian Nat Prod Res
; 24(6): 596-602, 2022 Jun.
Article
em En
| MEDLINE
| ID: mdl-34292109
ABSTRACT
One new cycloartane-type triterpenoid, named macrobidoupoic acid A (as an C-24 epimeric mixture, 4a, 4 b), together with three known ones (1-3), were clarified by different chromatography from the M. bidoupensis whole plants. Triterpenoids (1, 3 & 4) were detected for the first time from the Macrosolen genus. Chemical structures of them were illuminated using HR-ESI-MS, and NMR (1 D & 2 D) assessments. The cytotoxic properties of triterpenoids (3 & 4) were examined against two human cancer cell lines (A549, and RD) by MTT assay. As results shown, triterpenoids (3 & 4) possessed moderate cytotoxic activity against A549 and RD cancer cells (IC50 ranged from 5.44 to 39.52 µM).
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
Idioma:
En
Revista:
J Asian Nat Prod Res
Ano de publicação:
2022
Tipo de documento:
Article