Urban green spaces and childhood leukemia incidence: A population-based case-control study in Madrid.
Environ Res
; 202: 111723, 2021 11.
Article
em En
| MEDLINE
| ID: mdl-34293306
ABSTRACT
BACKGROUND:
Childhood leukemia is the most common childhood cancer. To date, few risk factors related to predisposition have been identified; therefore, new hypotheses should be considered.OBJECTIVE:
To explore the possible relationship of residential proximity to urban green spaces on childhood leukemia.METHODS:
We conducted a population-based case control study in the metropolitan area of Madrid from 2000 to 2015. It included 383 incident cases and 1935 controls, individually matched by birth year, sex and area of residence. Using the geographical coordinates of the participants' home residences, we built a proxy for exposure with four distances (250 m, 500 m, 750 m and 1 km) to urban parks (UPs) and urban wooded areas (UWAs). We employed logistic regression models to determinate the effect of them on childhood leukemia adjusting for environmental and socio-demographic covariates.RESULTS:
we found a reduction in childhood leukemia incidence at a distance of 250 m from UPs (OR = 0.78; 95%CI = 0.62-0.98), as well as a reduction of the incidence in the Q3 and Q4 quintiles for exposure to UWAs, in the 250 m and 500 m buffers respectively (Q3 (250 m) OR = 0.69; 95%CI = 0.48-1.00; and, Q4 (500 m) OR = 0.69; 95%CI = 0.48-0.99).CONCLUSIONS:
Our results suggest a possible association between lower incidence of childhood leukemia and proximity to different forms of urban green space. This study is a first approach to the possible urban green space effects on childhood leukemia so is necessary to continue studying this spaces taking into account more individual data and other environmental risk factors.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Leucemia
/
Parques Recreativos
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Environ Res
Ano de publicação:
2021
Tipo de documento:
Article