Mechanisms that allow vaccination against an oncolytic vesicular stomatitis virus-encoded transgene to enhance safety without abrogating oncolysis.

AuYeung, Amanda W K; Mould, Robert C; Stegelmeier, Ashley A; van Vloten, Jacob P; Karimi, Khalil; Woods, J Paul; Petrik, James J; Wood, Geoffrey A; Bridle, Byram W

AuYeung, Amanda W K; Mould, Robert C; Stegelmeier, Ashley A; van Vloten, Jacob P; Karimi, Khalil; Woods, J Paul; Petrik, James J; Wood, Geoffrey A; Bridle, Byram W.

Afiliação

AuYeung AWK; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Mould RC; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Stegelmeier AA; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
van Vloten JP; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Karimi K; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Woods JP; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Petrik JJ; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Wood GA; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Bridle BW; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada. bbridle@uoguelph.ca.

Sci Rep ; 11(1): 15290, 2021 07 27.

Article em En | MEDLINE | ID: mdl-34315959

Assuntos

Vírus Oncolíticos/genética; Transgenes; Vesiculovirus/genética; Vacinas Virais/imunologia; Animais; Camundongos; Vacinas Virais/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Virais / Vesiculovirus / Transgenes / Vírus Oncolíticos Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article

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