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Non-invasive vagal nerve stimulation enhances cognitive emotion regulation.
De Smet, Stefanie; Baeken, Chris; Seminck, Nina; Tilleman, Jozefien; Carrette, Evelien; Vonck, Kristl; Vanderhasselt, Marie-Anne.
Afiliação
  • De Smet S; Department of Head and Skin, Psychiatry and Medical Psychology, Ghent University Hospital, Ghent University, Ghent, Belgium; Ghent Experimental Psychiatry (GHEP) Lab, Ghent, Belgium. Electronic address: stefanie.desmet@ugent.be.
  • Baeken C; Department of Head and Skin, Psychiatry and Medical Psychology, Ghent University Hospital, Ghent University, Ghent, Belgium; Ghent Experimental Psychiatry (GHEP) Lab, Ghent, Belgium; Department of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium; Department of Psychiatry
  • Seminck N; Ghent Experimental Psychiatry (GHEP) Lab, Ghent, Belgium.
  • Tilleman J; Ghent Experimental Psychiatry (GHEP) Lab, Ghent, Belgium.
  • Carrette E; Department of Head and Skin, Psychiatry and Medical Psychology, Ghent University Hospital, Ghent University, Ghent, Belgium; Department of Head and Skin, Neurology, 4 Brain, Ghent University Hospital, Ghent, Belgium.
  • Vonck K; Department of Head and Skin, Neurology, 4 Brain, Ghent University Hospital, Ghent, Belgium.
  • Vanderhasselt MA; Department of Head and Skin, Psychiatry and Medical Psychology, Ghent University Hospital, Ghent University, Ghent, Belgium; Ghent Experimental Psychiatry (GHEP) Lab, Ghent, Belgium; Department of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium.
Behav Res Ther ; 145: 103933, 2021 10.
Article em En | MEDLINE | ID: mdl-34332299
ABSTRACT
Transcutaneous auricular vagus nerve stimulation (taVNS) has been proposed as a potential new tool in the treatment of major depressive disorder. Prior studies have demonstrated that taVNS enhances cognitive control and is able to modulate brain activity in key regions involved in cognitive emotion regulation, such as the anterior cingulate and medial prefrontal cortex, which is known to be impaired in depressed patients. Preclinical studies are lacking but may provide important insights into the working mechanisms of taVNS on cognitive emotion regulatory processes. In this between-subject study, 83 healthy subjects underwent a single-session of active taVNS or sham stimulation, after which cognitive reappraisal was examined using a computer-based cognitive emotion regulation task. Our results indicate that participants receiving active taVNS, compared to sham, were better at using cognitive reappraisal and rated their response to emotion-eliciting pictures as less intense. Yet, even though we found significant differences in behavioral measures of cognitive emotion regulation, no differences between groups were found in terms of physiological responses to the emotional stimuli. Overall, these findings suggest a positive effect of taVNS on the cognitive reappraisal of emotions, but future studies assessing objective measures of neural activity during cognitive emotion regulation following taVNS are warranted.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estimulação Elétrica Nervosa Transcutânea / Transtorno Depressivo Maior / Estimulação do Nervo Vago / Regulação Emocional Limite: Humans Idioma: En Revista: Behav Res Ther Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estimulação Elétrica Nervosa Transcutânea / Transtorno Depressivo Maior / Estimulação do Nervo Vago / Regulação Emocional Limite: Humans Idioma: En Revista: Behav Res Ther Ano de publicação: 2021 Tipo de documento: Article