IL-6 Generated from Human Hematopoietic Stem and Progenitor Cells through TLR4 Signaling Promotes Emergency Granulopoiesis by Regulating Transcription Factor Expression.

Sasaki, Yumi; Guo, Yong-Mei; Goto, Tatsufumi; Ubukawa, Kumi; Asanuma, Ken; Kobayashi, Isuzu; Sawada, Kenichi; Wakui, Hideki; Takahashi, Naoto

Sasaki, Yumi; Guo, Yong-Mei; Goto, Tatsufumi; Ubukawa, Kumi; Asanuma, Ken; Kobayashi, Isuzu; Sawada, Kenichi; Wakui, Hideki; Takahashi, Naoto.

Afiliação

Sasaki Y; Department of Life Science, Graduate School of Engineering Science, Akita University, Akita, Japan.
Guo YM; Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan; kakueibai@yahoo.co.jp.
Goto T; Department of Life Science, Graduate School of Engineering Science, Akita University, Akita, Japan.
Ubukawa K; Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Asanuma K; Division of Radio Isotope, Bioscience Education and Research Support Center, Akita University School of Medicine, Akita, Japan; and.
Kobayashi I; Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Sawada K; Medical Corporation Hokubukai Utsukushigaoka Hospital, Hokkaido, Japan.
Wakui H; Department of Life Science, Graduate School of Engineering Science, Akita University, Akita, Japan.
Takahashi N; Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.

J Immunol ; 207(4): 1078-1086, 2021 08 15.

Article em En | MEDLINE | ID: mdl-34341172

Assuntos

Granulócitos/metabolismo; Células-Tronco Hematopoéticas/metabolismo; Interleucina-6/metabolismo; Transdução de Sinais/fisiologia; Células-Tronco/metabolismo; Receptor 4 Toll-Like/metabolismo; Adaptação Fisiológica/fisiologia; Antígenos CD34/metabolismo; Medula Óssea/metabolismo; Proteína beta Intensificadora de Ligação a CCAAT/metabolismo; Diferenciação Celular/fisiologia; Citocinas/metabolismo; Regulação da Expressão Gênica/fisiologia; Células Precursoras de Granulócitos/metabolismo; Transplante de Células-Tronco Hematopoéticas/métodos; Humanos; Monócitos/metabolismo; Mielopoese/fisiologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco / Células-Tronco Hematopoéticas / Transdução de Sinais / Interleucina-6 / Receptor 4 Toll-Like / Granulócitos Limite: Humans Idioma: En Revista: J Immunol Ano de publicação: 2021 Tipo de documento: Article

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