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Cell-based assays and molecular simulation reveal that the anti-cancer harmine is a specific matrix metalloproteinase-3 (MMP-3) inhibitor.
Chin, Li-Te; Liu, Ke-Wei; Chen, Yi-Han; Hsu, Shu-Ching; Huang, Lin.
Afiliação
  • Chin LT; Department of Microbiology, Immunology and Biopharmaceuticals, National Chiayi University, Chiayi City, 60004, Taiwan, ROC; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei City, 11400, Taiwan, ROC.
  • Liu KW; Department of Microbiology, Immunology and Biopharmaceuticals, National Chiayi University, Chiayi City, 60004, Taiwan, ROC.
  • Chen YH; Department of Microbiology, Immunology and Biopharmaceuticals, National Chiayi University, Chiayi City, 60004, Taiwan, ROC.
  • Hsu SC; Synergy Biomedical Corp., Hsinchu City, 30054, Taiwan, ROC.
  • Huang L; Synergy Biomedical Corp., Hsinchu City, 30054, Taiwan, ROC. Electronic address: x0915369728@gmail.com.
Comput Biol Chem ; 94: 107556, 2021 Oct.
Article em En | MEDLINE | ID: mdl-34384998
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metaloproteinase 3 da Matriz / Inibidores Enzimáticos / Simulação de Acoplamento Molecular / Harmina / Antineoplásicos Limite: Humans Idioma: En Revista: Comput Biol Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metaloproteinase 3 da Matriz / Inibidores Enzimáticos / Simulação de Acoplamento Molecular / Harmina / Antineoplásicos Limite: Humans Idioma: En Revista: Comput Biol Chem Ano de publicação: 2021 Tipo de documento: Article