Prebiotic characteristics of arabinogalactans during in vitro fermentation through multi-omics analysis.
Food Chem Toxicol
; 156: 112522, 2021 Oct.
Article
em En
| MEDLINE
| ID: mdl-34438010
ABSTRACT
BACKGROUND AND OBJECTIVES:
Dietary fibers have beneficial effects on human health through the interaction with gut microbiota. Larch wood arabinogalactan (LA-AG) is one kind of complex soluble dietary fibers that may be utilized by human gut microbiota. METHODS ANDRESULTS:
In this study, the LA-AG degradation by gut microbiota were characterized by investigating the change of LA-AG, microbiota composition, and the production of short-chain fatty acids (SCFAs), lactic acid, succinic acid, as well as volatile organic metabolites. During the fermentation, pH decreased continuously, along with the organic acids (especially acetic acid and lactic acid) accumulating. LA-AG was degraded by gut microbiota then some beneficial metabolites were produced. In addition, LA-AG inhibited the proliferation of some gut microbiota (Unclassified_Enterobacteriaceae and Citrobacter) and the accumulation of some metabolites (Sulfide and indole) released by gut microbiota.CONCLUSION:
LA-AG was partly fermentable fibers with prebiotic potential for human gut health.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Prebióticos
/
Microbioma Gastrointestinal
/
Galactanos
Limite:
Humans
Idioma:
En
Revista:
Food Chem Toxicol
Ano de publicação:
2021
Tipo de documento:
Article