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CCT245718, a dual FLT3/Aurora A inhibitor overcomes D835Y-mediated resistance to FLT3 inhibitors in acute myeloid leukaemia cells.
Tariq, Muhammad Usama; Furqan, Muhammad; Parveen, Hira; Ullah, Rahim; Muddassar, Muhammad; Saleem, Rahman Shah Zaib; Bavetsias, Vassilios; Linardopoulos, Spiros; Faisal, Amir.
Afiliação
  • Tariq MU; Department of Biology, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore, Pakistan.
  • Furqan M; Department of Biology, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore, Pakistan.
  • Parveen H; Department of Biology, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore, Pakistan.
  • Ullah R; Department of Biology, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore, Pakistan.
  • Muddassar M; Department of Biosciences, COMSATS University Islamabad, Islamabad, Pakistan.
  • Saleem RSZ; Department of Chemistry and Chemical Engineering, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore, Pakistan.
  • Bavetsias V; Cancer Research UK, Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK.
  • Linardopoulos S; Cancer Research UK, Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK.
  • Faisal A; Breast Cancer Now, Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.
Br J Cancer ; 125(7): 966-974, 2021 09.
Article em En | MEDLINE | ID: mdl-34446858
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Resistencia a Medicamentos Antineoplásicos / Tirosina Quinase 3 Semelhante a fms / Aurora Quinase A / Imidazóis Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Resistencia a Medicamentos Antineoplásicos / Tirosina Quinase 3 Semelhante a fms / Aurora Quinase A / Imidazóis Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2021 Tipo de documento: Article