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Bilateral Breast Radiation Associated Angiosarcoma After Radiotherapy for Bilateral Invasive Ductal Adenocarcinoma.
Vin Chang, Guy; Xie, Chencheng; Shahid, Mahum; Draine, Jillian; Alpers, Josie; Reindl, Bailey; McHale, Michael.
Afiliação
  • Vin Chang G; Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
  • Xie C; Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
  • Shahid M; Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
  • Draine J; Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
  • Alpers J; Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
  • Reindl B; University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
  • McHale M; Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
S D Med ; 74(6): 260-263, 2021 Jun.
Article em En | MEDLINE | ID: mdl-34449165
ABSTRACT
Angiosarcoma is a rare, highly malignant endothelial cell carcinoma. Radiotherapy on breast cancer increases the risk of developing an angiosarcoma. We report an extremely rare case of bilateral breast radiation-associated angiosarcoma (RAA). Patient had a strong breast cancer family history, and genetic testing identified KRAS, PIK3CA, RPTOR, and VHL mutation, along with MYC amplification. The overall prognosis of RAA is poor as RAA is characterized by early metastasis, frequent local recurrence, and short overall survival time. The patient eventually passed away because of breast cancer metastasis to the lung and liver.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Adenocarcinoma / Hemangiossarcoma Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: S D Med Ano de publicação: 2021 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Adenocarcinoma / Hemangiossarcoma Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: S D Med Ano de publicação: 2021 Tipo de documento: Article