HOXD8 inhibits the proliferation and migration of triple-negative breast cancer cells and induces apoptosis in them through regulation of AKT/mTOR pathway.

Zhang, Yixin; Yu, Yu; Su, Xiaobao; Lu, Yuqin

Zhang, Yixin; Yu, Yu; Su, Xiaobao; Lu, Yuqin.

Afiliação

Zhang Y; Department of Thyroid and Breast Surgery, the Affiliated Peoples Hospital of Ningbo University, Ningbo City, Zhejiang Province, 315040, China.
Yu Y; Department of Thyroid and Breast Surgery, the Affiliated Peoples Hospital of Ningbo University, Ningbo City, Zhejiang Province, 315040, China.
Su X; Department of Thyroid and Breast Surgery, the Affiliated Peoples Hospital of Ningbo University, Ningbo City, Zhejiang Province, 315040, China.
Lu Y; Department of Nail Breast Surgery, Huai'an Second People's Hospital, Huai'an City, Jiangsu Province, 223002, China. Electronic address: luyuqin_666@163.com.

Reprod Biol ; 21(4): 100544, 2021 Dec.

Article em En | MEDLINE | ID: mdl-34454307

Assuntos

Proteínas de Homeodomínio/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Fatores de Transcrição/metabolismo; Neoplasias de Mama Triplo Negativas/metabolismo; Animais; Apoptose; Linhagem Celular Tumoral; Humanos; Camundongos Endogâmicos BALB C; Camundongos Nus; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

AKT/mTOR; Apoptosis; HOXD8; Progression; TNBC

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas de Homeodomínio / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Neoplasias de Mama Triplo Negativas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Reprod Biol Ano de publicação: 2021 Tipo de documento: Article

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