Conjugated Coordination Porphyrin-based Nanozymes for Photo-/Sono-Augmented Biocatalytic and Homologous Tumor Treatments.

Du, Fangxue; Liu, Luchang; Li, Ling; Huang, Jianbo; Wang, Liyun; Tang, Yuanjiao; Ke, Bowen; Song, Li; Cheng, Chong; Ma, Lang; Qiu, Li

Du, Fangxue; Liu, Luchang; Li, Ling; Huang, Jianbo; Wang, Liyun; Tang, Yuanjiao; Ke, Bowen; Song, Li; Cheng, Chong; Ma, Lang; Qiu, Li.

Afiliação

Du F; Department of Ultrasound, National Clinical Research Center for Geriatrics, West China Hospital, College of Polymer Science and Engineering, Sichuan University, Chengdu 610041, China.
Liu L; Department of Ultrasound, National Clinical Research Center for Geriatrics, West China Hospital, College of Polymer Science and Engineering, Sichuan University, Chengdu 610041, China.
Li L; Department of Ultrasound, National Clinical Research Center for Geriatrics, West China Hospital, College of Polymer Science and Engineering, Sichuan University, Chengdu 610041, China.
Huang J; Department of Ultrasound, Sichuan Key Laboratory of Medical Imaging, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China.
Wang L; Department of Ultrasound, National Clinical Research Center for Geriatrics, West China Hospital, College of Polymer Science and Engineering, Sichuan University, Chengdu 610041, China.
Tang Y; Department of Ultrasound, National Clinical Research Center for Geriatrics, West China Hospital, College of Polymer Science and Engineering, Sichuan University, Chengdu 610041, China.
Ke B; Department of Ultrasound, National Clinical Research Center for Geriatrics, West China Hospital, College of Polymer Science and Engineering, Sichuan University, Chengdu 610041, China.
Song L; Laboratory of Anesthesia and Critical Care Medicine, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Cheng C; Department of Pain Management, West China Hospital, Sichuan University, Chengdu 610041, China.
Ma L; Department of Ultrasound, National Clinical Research Center for Geriatrics, West China Hospital, College of Polymer Science and Engineering, Sichuan University, Chengdu 610041, China.
Qiu L; Department of Chemistry and Biochemistry, Freie Universität Berlin, Takustrasse 3, 14195, Berlin, Germany.

ACS Appl Mater Interfaces ; 13(35): 41485-41497, 2021 Sep 08.

Article em En | MEDLINE | ID: mdl-34455796

Assuntos

Antineoplásicos/uso terapêutico; Nanopartículas/uso terapêutico; Neoplasias/tratamento farmacológico; Porfirinas/uso terapêutico; Radiossensibilizantes/uso terapêutico; Animais; Antineoplásicos/química; Antineoplásicos/efeitos da radiação; Catálise; Membrana Celular/química; Complexos de Coordenação/química; Complexos de Coordenação/efeitos da radiação; Complexos de Coordenação/uso terapêutico; Células Endoteliais da Veia Umbilical Humana; Humanos; Radical Hidroxila/metabolismo; Luz; Camundongos; Nanopartículas/química; Nanopartículas/efeitos da radiação; Porfirinas/química; Porfirinas/efeitos da radiação; Radiossensibilizantes/química; Radiossensibilizantes/efeitos da radiação; Ondas Ultrassônicas

Palavras-chave

biocatalytic and homologous nanoagents; biocatalytic tumor therapies; malignant melanoma; porphyrin-based nanozymes; reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Porfirinas / Radiossensibilizantes / Nanopartículas / Neoplasias / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: ACS Appl Mater Interfaces Ano de publicação: 2021 Tipo de documento: Article

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