Gallic acid enhances pirarubicin­induced anticancer in living K562 and K562/Dox leukemia cancer cells through cellular energetic state impairment and P­glycoprotein inhibition.

Aye, Khin Thenu; Wattanapongpitak, Sakornniya; Supawat, Benjamaporn; Kothan, Suchart; Udomtanakunchai, Chatchanok; Tima, Singkome; Pan, Jie; Tungjai, Montree

Gallic acid enhances pirarubicininduced anticancer in living K562 and K562/Dox leukemia cancer cells through cellular energetic state impairment and Pglycoprotein inhibition.

Aye, Khin Thenu; Wattanapongpitak, Sakornniya; Supawat, Benjamaporn; Kothan, Suchart; Udomtanakunchai, Chatchanok; Tima, Singkome; Pan, Jie; Tungjai, Montree.

Afiliação

Aye KT; Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Wattanapongpitak S; Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Supawat B; Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Kothan S; Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Udomtanakunchai C; Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Tima S; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Pan J; Center of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Tungjai M; Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.

Oncol Rep ; 46(4)2021 Oct.

Article em En | MEDLINE | ID: mdl-34476509

Assuntos

Membro 1 da Subfamília B de Cassetes de Ligação de ATP/metabolismo; Sobrevivência Celular/efeitos dos fármacos; Doxorrubicina/análogos & derivados; Resistencia a Medicamentos Antineoplásicos/efeitos dos fármacos; Ácido Gálico/farmacologia; Leucemia/tratamento farmacológico; Antineoplásicos/farmacologia; Doxorrubicina/farmacologia; Sinergismo Farmacológico; Humanos; Células K562

Palavras-chave

Pglycoprotein; cancer; gallic acid; multidrug resistance; pirarubicin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia / Doxorrubicina / Sobrevivência Celular / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Resistencia a Medicamentos Antineoplásicos / Ácido Gálico Limite: Humans Idioma: En Revista: Oncol Rep Ano de publicação: 2021 Tipo de documento: Article

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