PFOA regulate adenosine receptors and downstream concentration-response cAMP-PKA pathway revealed by integrated omics and molecular dynamics analyses.

Li, Xin; Chen, Lei; Zhou, Haitao; Wang, Jie; Zhao, Chunyan; Pang, Xinyue

Li, Xin; Chen, Lei; Zhou, Haitao; Wang, Jie; Zhao, Chunyan; Pang, Xinyue.

Afiliação

Li X; College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, China; National Demonstration Center for Experimental Food Processing and Safety Education, Luoyang 471000, China.
Chen L; College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, China.
Zhou H; Neurology Department, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.
Wang J; College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, China.
Zhao C; School of Pharmacy, Lanzhou University, Lanzhou 730000, China. Electronic address: zhaochy07@lzu.edu.cn.
Pang X; College of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471023, China. Electronic address: pangxy78@haust.edu.cn.

Sci Total Environ ; 803: 149910, 2022 Jan 10.

Article em En | MEDLINE | ID: mdl-34500266

Assuntos

Fluorocarbonos; Proteômica; Feminino; Fluorocarbonos/toxicidade; Humanos; Simulação de Dinâmica Molecular; Receptor A1 de Adenosina

Palavras-chave

Adenosine receptor; Concentration-response; PFOA; cAMP signaling pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteômica / Fluorocarbonos Limite: Female / Humans Idioma: En Revista: Sci Total Environ Ano de publicação: 2022 Tipo de documento: Article

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