Allicin May Promote Reversal of T-Cell Dysfunction in Periodontitis via the <i>PD-1</i> Pathway.

Patil, Shankargouda; Sayed, Mohammed E; Mugri, Maryam H; Alsharif, Khalaf F; Salman, Arif; Bhandi, Shilpa; Baeshen, Hosam Ali; Balaji, Thodur Madapusi; Yadalam, Pradeep Kumar; Varadarajan, Saranya; Radha, R Srimathi R; Awan, Kamran Habib; Patil, Vikrant R; Raj, A Thirumal

Allicin May Promote Reversal of T-Cell Dysfunction in Periodontitis via the PD-1 Pathway.

Patil, Shankargouda; Sayed, Mohammed E; Mugri, Maryam H; Alsharif, Khalaf F; Salman, Arif; Bhandi, Shilpa; Baeshen, Hosam Ali; Balaji, Thodur Madapusi; Yadalam, Pradeep Kumar; Varadarajan, Saranya; Radha, R Srimathi R; Awan, Kamran Habib; Patil, Vikrant R; Raj, A Thirumal.

Afiliação

Patil S; Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan 45412, Saudi Arabia.
Sayed ME; Department of Prosthetic Dental Sciences, College of Dentistry, Jazan University, Jazan 45412, Saudi Arabia.
Mugri MH; Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan 45412, Saudi Arabia.
Alsharif KF; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Salman A; Department of Periodontics, School of Dentistry, West Virginia University, P.O. Box 9490, Morgantown, WV 26506, USA.
Bhandi S; Department of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan 45412, Saudi Arabia.
Baeshen HA; Department of Orthodontics, College of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Balaji TM; Tagore Dental College and Hospital, Chennai 600127, India.
Yadalam PK; Department of Periodontics, Adhi Parashakthi Dental College, Melvaruvathur 603319, India.
Varadarajan S; Department of Oral Pathology and Microbiology, Sri Venkateswara Dental College and Hospital, Chennai 600130, India.
Radha RSR; SRM College of Pharmacy, Kancheepuram 603203, India.
Awan KH; College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT 84095, USA.
Patil VR; Biogenre Private Limited, Pune 412105, India.
Raj AT; Department of Oral Pathology and Microbiology, Sri Venkateswara Dental College and Hospital, Chennai 600130, India.

Int J Mol Sci ; 22(17)2021 Aug 25.

Article em En | MEDLINE | ID: mdl-34502071

Assuntos

Antígeno B7-H1/metabolismo; Dissulfetos/farmacologia; Periodontite/metabolismo; Ácidos Sulfínicos/farmacologia; Linfócitos T/efeitos dos fármacos; Antígenos CD/genética; Antígenos CD/metabolismo; Antígeno B7-H1/química; Sítios de Ligação; Células Cultivadas; Quimiocina CCL2/genética; Quimiocina CCL2/metabolismo; Quimiocina CXCL6/genética; Quimiocina CXCL6/metabolismo; Dissulfetos/química; Receptor Celular 2 do Vírus da Hepatite A/genética; Receptor Celular 2 do Vírus da Hepatite A/metabolismo; Humanos; Interferon gama/genética; Interferon gama/metabolismo; Interleucina-6/genética; Interleucina-6/metabolismo; Ligação Proteica; Ácidos Sulfínicos/química; Linfócitos T/metabolismo; Fator de Necrose Tumoral alfa/genética; Fator de Necrose Tumoral alfa/metabolismo; Proteína do Gene 3 de Ativação de Linfócitos

Palavras-chave

T lymphocytes; allicin; gingival crevicular fluid; periodontitis

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Periodontite / Ácidos Sulfínicos / Linfócitos T / Dissulfetos / Antígeno B7-H1 Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article

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