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Discovery of Novel Pterostilbene-Based Derivatives as Potent and Orally Active NLRP3 Inflammasome Inhibitors with Inflammatory Activity for Colitis.
Chen, Liu Zeng; Zhang, Xing Xing; Liu, Ming Ming; Wu, Jing; Ma, Duo; Diao, Liang Zhuo; Li, Qingshan; Huang, Yan Shuang; Zhang, Rui; Ruan, Ban Feng; Liu, Xin Hua.
Afiliação
  • Chen LZ; School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, P.R. China.
  • Zhang XX; Key Lab of Biofabrication of Anhui Higher Education, Hefei University, Hefei 230601, P.R. China.
  • Liu MM; School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, P.R. China.
  • Wu J; School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, P.R. China.
  • Ma D; School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, P.R. China.
  • Diao LZ; School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, P.R. China.
  • Li Q; School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, P.R. China.
  • Huang YS; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230059, P.R. China.
  • Zhang R; School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, P.R. China.
  • Ruan BF; School of Pharmacy, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei 230032, P.R. China.
  • Liu XH; Key Lab of Biofabrication of Anhui Higher Education, Hefei University, Hefei 230601, P.R. China.
J Med Chem ; 64(18): 13633-13657, 2021 09 23.
Article em En | MEDLINE | ID: mdl-34506712
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Colite / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Med Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Colite / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Med Chem Ano de publicação: 2021 Tipo de documento: Article