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The RAI-6 Questionnaire: A New Screening Questionnaire to Monitor Complications of Radioiodine Treatment.
Buchholzer, Samanta; Thakachy Subha, Sethu; Tchérémissinoff, Livia; Boselie, Franciscus; Triponez, Frédéric; Faure, Frédéric; Lopez, Jean-Michel; Borner, Urs; Kleinjung, Tobias; Seebach, Jörg D; Dulguerov, Pavel; Marchal, Francis.
Afiliação
  • Buchholzer S; Department of Maxillofacial Surgery and Oral Medicine and Pathology, Geneva University Hospitals, Geneva, Switzerland.
  • Thakachy Subha S; Department of Surgery/ENT, Universiti Putra Malaysia (UPM), Serdang, Malaysia.
  • Tchérémissinoff L; European Sialendoscopy Training Center, Geneva, Switzerland.
  • Boselie F; Department of Otolaryngology-Head and Neck Surgery, University Hospitals of Geneva, Geneva, Switzerland.
  • Triponez F; Department of Thoracic Surgery, University Hospitals of Geneva, Geneva, Switzerland.
  • Faure F; Department of Otolaryngology-Head and Neck Surgery, University Hospitals of Lyon, Lyon, France.
  • Lopez JM; Department of Otolaryngology-Head and Neck Surgery, Perpignan Hospital, Perpignan, France.
  • Borner U; Department of Otolaryngology-Head and Neck Surgery, University Hospitals of Bern, Bern, Switzerland.
  • Kleinjung T; Department of Otolaryngology-Head and Neck Surgery, University Hospitals of Zürich, Zurich, Switzerland.
  • Seebach JD; Division of Allergy and Immunology, Department of Medicine, University Hospitals of Geneva, Geneva, Switzerland.
  • Dulguerov P; Hôpital de la Tour, Geneva University, Geneva, Switzerland.
  • Marchal F; Department of Otolaryngology-Head and Neck Surgery, University Hospitals of Geneva, Geneva, Switzerland.
Front Surg ; 8: 641945, 2021.
Article em En | MEDLINE | ID: mdl-34540883
ABSTRACT

Objective:

The aim of this study is to develop a simple and efficient screening questionnaire to be able to routinely monitor potential radioiodine therapy-induced complications. Materials and

Methods:

A new radioiodine 6 (RAI-6) questionnaire containing six questions adressing salivary, ocular, and nasal symptoms as well as quality of life was developed. Validation of the RAI-6 questionnaire was assessed with a group of fifty-four patients diagnosed with differentiated thyroid carcinoma treated post-operatively with radioiodine therapy, and in a group of fifty healthy volunteers. The patient's group was subdivided into subgroups according to the radioiodine dose received 23 patients received less or 30 mCi, 28 patients received 100 mCi, and three patients received between 200 and 300 mCi. We asked the patients to complete the RAI-6 questionnaire in a retrospective manner, regarding their situation before radioiodine therapy and regarding their actual symptoms after radioiodine therapy. The time needed to complete the RAI-6 was also assessed both in patients and in healthy volunteers.

Results:

The mean post radioiodine treatment RAI-6 score were significantly higher than the mean pre radioiodine RAI-6 scores (p < 0.001) and the scores of healthy participants (p < 0.001). The mean total RAI-6 scores increased significantly with increasing radioiodine dose. A total mean RAI-6 score of each question was also analysed and revealed that ocular and nasal discomfort as well as quality of life were the items which affected the patients most after radioiodine treatment. The mean time to fill the RAI-6 questionnaire was 2 min for patients and 49 s for healthy volunteers.

Conclusion:

The RAI-6 represents a new questionnaire which is easy and quick to complete. This simple screening tool can be recommended for general clinical practise and further epidemiological research.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Screening_studies Aspecto: Patient_preference Idioma: En Revista: Front Surg Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Screening_studies Aspecto: Patient_preference Idioma: En Revista: Front Surg Ano de publicação: 2021 Tipo de documento: Article