Social-like responses are inducible in asocial Mexican cavefish despite the exhibition of strong repetitive behavior.
Elife
; 102021 09 20.
Article
em En
| MEDLINE
| ID: mdl-34542411
ABSTRACT
Social behavior is a hallmark of complex animal systems; however, some species appear to have secondarily lost this social ability. In these non-social species, whether social abilities are permanently lost or suppressed is unclear. The blind cavefish Astyanax mexicanus is known to be asocial. Here, we reveal that cavefish exhibited social-like interactions in familiar environments but suppressed these interactions in stress-associated unfamiliar environments. Furthermore, the level of suppression in sociality was positively correlated with that of stereotypic repetitive behavior, as seen in mammals. Treatment with a human antipsychotic drug targeting the dopaminergic system induced social-like interactions in cavefish, even in unfamiliar environments, while reducing repetitive behavior. Overall, these results suggest that the antagonistic association between repetitive and social-like behaviors is deeply shared from teleosts through mammals.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Comportamento Social
/
Comportamento Estereotipado
/
Comportamento Animal
/
Characidae
Aspecto:
Determinantes_sociais_saude
Limite:
Animals
País/Região como assunto:
Mexico
Idioma:
En
Revista:
Elife
Ano de publicação:
2021
Tipo de documento:
Article