The GLU-10: a validated ten-point score to identify poorly instructed celiac patients in need of dietary interventions.
Minerva Gastroenterol (Torino)
; 68(1): 91-97, 2022 Mar.
Article
em En
| MEDLINE
| ID: mdl-34547859
ABSTRACT
BACKGROUND:
A standard tool to assess patients' knowledge about gluten and the gluten-free diet (GFD) is lacking.METHODS:
We aimed to develop and validate a questionnaire to assess GFD knowledge. A 10-point questionnaire (GLU10) covering different aspects of knowledge about gluten content in food/non-food products and the gluten-free living was developed. To validate this questionnaire, it was administered to adult celiac patients already instructed on gluten and the GFD and non-celiac controls. Patients were prospectively recruited at our Gastroenterology Outpatient Clinic between August 2020 and February 2021.RESULTS:
One hundred and six patients (52 celiac patients and 54 controls) participated in the validation phase. Celiac patients scored significantly higher than controls on the GLU10 Questionnaire (median 6 points vs. 2 points, P<0.001). Higher self-reported knowledge of the GFD was related to a higher score (P<0.001). ROC curve confirmed the ability of the GLU10 Questionnaire to discriminate between subjects with good and poor GFD knowledge (AUC=0.94, 95% CI 0.90-0.98). A score of 5 was identified as the best cut-off (sensitivity 80.8%, specificity 94.4%). On multivariable logistic regression analysis, being a celiac patient (P<0.001) and having a university degree (P=0.04) were associated to a high GLU10 Score (≥5).CONCLUSIONS:
GLU10 is the first validated questionnaire for assessing knowledge of a GFD in celiac patients and the general population.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença Celíaca
/
Conhecimentos, Atitudes e Prática em Saúde
/
Dieta Livre de Glúten
Tipo de estudo:
Prognostic_studies
/
Qualitative_research
Limite:
Adult
/
Humans
Idioma:
En
Revista:
Minerva Gastroenterol (Torino)
Ano de publicação:
2022
Tipo de documento:
Article