Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay.

Tzanova, Martina M; Randelov, Elizabeta; Stein, Paul C; Hiorth, Marianne; di Cagno, Massimiliano Pio

Tzanova, Martina M; Randelov, Elizabeta; Stein, Paul C; Hiorth, Marianne; di Cagno, Massimiliano Pio.

Afiliação

Tzanova MM; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Norway.
Randelov E; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Norway.
Stein PC; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.
Hiorth M; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Norway.
di Cagno MP; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Norway. Electronic address: m.p.d.cagno@farmasi.uio.no.

Int J Pharm ; 608: 121116, 2021 Oct 25.

Article em En | MEDLINE | ID: mdl-34555476

Assuntos

Compreensão; Preparações Farmacêuticas; Difusão; Interações Hidrofóbicas e Hidrofílicas; Absorção Intestinal; Permeabilidade

Palavras-chave

Dynamic viscosity; Permeability; Permeapad®; Poly(ethylene glycol) (PEG); UVvisible localized spectroscopy; Unstirred water layer

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Texto completo: 1 Coleções: 01-internacional Temas: Acesso_medicamentos_insumos_estrategicos Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Compreensão Tipo de estudo: Prognostic_studies Idioma: En Revista: Int J Pharm Ano de publicação: 2021 Tipo de documento: Article

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