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Miniaturized Forced Degradation of Therapeutic Proteins and ADCs by Agitation-Induced Aggregation Using Orbital Shaking of Microplates.
Johann, Florian; Wöll, Steffen; Winzer, Matthias; Snell, Jared; Valldorf, Bernhard; Gieseler, Henning.
Afiliação
  • Johann F; Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Department of Pharmaceutics, Freeze Drying Focus Group (FDFG), Cauerstraße 4, 91058 Erlangen, Germany; Merck KGaA, Department of Pharmaceutical Technologies, Frankfurter Straße 250, 64293 Darmstadt, Germany.
  • Wöll S; Merck KGaA, Department of Pharmaceutical Technologies, Frankfurter Straße 250, 64293 Darmstadt, Germany.
  • Winzer M; Merck KGaA, Department of Pharmaceutical Technologies, Frankfurter Straße 250, 64293 Darmstadt, Germany.
  • Snell J; EMD Serono Research and Development Institute, Department of Pharmaceutical Technologies, 45A Middlesex Turnpike, Billerica, MA 01821, USA.
  • Valldorf B; Merck KGaA, Department of Pharmaceutical Technologies, Frankfurter Straße 250, 64293 Darmstadt, Germany.
  • Gieseler H; Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Department of Pharmaceutics, Freeze Drying Focus Group (FDFG), Cauerstraße 4, 91058 Erlangen, Germany; GILYOS GmbH, Friedrich-Bergius-Ring 15, 97076 Würzburg, Germany. Electronic address: info@gilyos.com.
J Pharm Sci ; 111(5): 1401-1413, 2022 05.
Article em En | MEDLINE | ID: mdl-34563536
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Excipientes Tipo de estudo: Guideline Idioma: En Revista: J Pharm Sci Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Excipientes Tipo de estudo: Guideline Idioma: En Revista: J Pharm Sci Ano de publicação: 2022 Tipo de documento: Article