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Clinical biomarkers in soft tissue sarcoma A comprehensive review of current soft tissue sarcoma biomarkers.
Sharma, Soumya R; Paonessa, Nadia E; Casadei, Lucia; Costas De Faria, Fernanda; Pollock, Raphael E; Grignol, Valerie.
Afiliação
  • Sharma SR; James Cancer Hospital Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Paonessa NE; James Cancer Hospital Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Casadei L; James Cancer Hospital Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Costas De Faria F; James Cancer Hospital Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Pollock RE; Department of Surgery, Division of Surgical Oncology, The Ohio State University, Columbus, Ohio, USA.
  • Grignol V; Department of Surgery, Division of Surgical Oncology, The Ohio State University, Columbus, Ohio, USA.
J Surg Oncol ; 125(2): 239-245, 2022 Feb.
Article em En | MEDLINE | ID: mdl-34586640
ABSTRACT
Soft tissue sarcomas (STS) are a heterogeneous group of tumors that arise from mesenchymal tissue. Investigation at the molecular level has been challenging due to the rarity of STS and the number of histologic subtypes. However, recent research has provided new insight into potential genomic, proteomic, and immunological biomarkers of STS. The identification of biomarkers can improve diagnosis, prognosis, and prediction of recurrence and treatment response. This review provides an understanding of biomarkers, discussing the current status of biomarker research in STS.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoma / Biomarcadores Tumorais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Surg Oncol Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoma / Biomarcadores Tumorais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Surg Oncol Ano de publicação: 2022 Tipo de documento: Article