The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases.

Altae-Tran, Han; Kannan, Soumya; Demircioglu, F Esra; Oshiro, Rachel; Nety, Suchita P; McKay, Luke J; Dlakic, Mensur; Inskeep, William P; Makarova, Kira S; Macrae, Rhiannon K; Koonin, Eugene V; Zhang, Feng

Altae-Tran, Han; Kannan, Soumya; Demircioglu, F Esra; Oshiro, Rachel; Nety, Suchita P; McKay, Luke J; Dlakic, Mensur; Inskeep, William P; Makarova, Kira S; Macrae, Rhiannon K; Koonin, Eugene V; Zhang, Feng.

Afiliação

Altae-Tran H; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Kannan S; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Demircioglu FE; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Oshiro R; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Nety SP; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
McKay LJ; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Dlakic M; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Inskeep WP; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Makarova KS; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Macrae RK; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Koonin EV; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Zhang F; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Science ; 374(6563): 57-65, 2021 Oct.

Article em En | MEDLINE | ID: mdl-34591643

Assuntos

Proteínas de Bactérias/genética; Proteína 9 Associada à CRISPR/genética; Proteínas Associadas a CRISPR/genética; Sistemas CRISPR-Cas/genética; Elementos de DNA Transponíveis/genética; Endodesoxirribonucleases/genética; Evolução Molecular; RNA Guia de Cinetoplastídeos; Sequência Conservada; Código Genético; Variação Genética; RNA não Traduzido/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Elementos de DNA Transponíveis / RNA Guia de Cinetoplastídeos / Evolução Molecular / Endodesoxirribonucleases / Proteínas Associadas a CRISPR / Sistemas CRISPR-Cas / Proteína 9 Associada à CRISPR Idioma: En Revista: Science Ano de publicação: 2021 Tipo de documento: Article

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