Risk of pneumothorax in pneumoconiosis patients in Taiwan: a retrospective cohort study.
BMJ Open
; 11(10): e054098, 2021 10 08.
Article
em En
| MEDLINE
| ID: mdl-34625418
ABSTRACT
OBJECTIVES:
This study was conducted to explore the association between pneumoconiosis and pneumothorax.DESIGN:
Retrospective cohort study.SETTING:
Nationwide population-based study using the Taiwan National Health Insurance Database.PARTICIPANTS:
A total of 2333 pneumoconiosis patients were identified (1935 patients for propensity score (PS)-matched cohort) and matched to 23 330 control subjects by age and sex (7740 subjects for PS-matched cohort). PRIMARY AND SECONDARY OUTCOMEMEASURES:
The incidence and the cumulative incidence of pneumothorax.RESULTS:
Both incidence and the cumulative incidence of pneumothorax were significantly higher in the pneumoconiosis patients as compared with the control subjects (p<0.0001). For multivariable Cox regression analysis adjusted for age, sex, residency, income level and other comorbidities, patients with pneumoconiosis exhibited a significantly higher risk of pneumothorax than those without pneumoconiosis (HR 3.05, 95% CI 2.18 to 4.28, p<0.0001). The male sex, heart disease, peripheral vascular disease, chronic pulmonary disease and connective tissue disease were risk factors for developing pneumothorax in pneumoconiosis patients.CONCLUSIONS:
Our study revealed a higher risk of pneumothorax in pneumoconiosis patients and suggested potential risk factors in these patients. Clinicians should be aware about the risk of pneumothorax in pneumoconiosis patients.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumoconiose
/
Pneumotórax
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
BMJ Open
Ano de publicação:
2021
Tipo de documento:
Article