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Olfactory disfunction and diabetic complications in type 2 diabetic patients: a pilot study.
Mozzanica, Francesco; Ferrulli, Anna; Vujosevic, Stela; Montuori, Alessandro; Cardella, Arianna; Preti, Andrea; Ambrogi, Federico; Schindler, Antonio; Terruzzi, Ileana; Ottaviani, Francesco; Luzi, Livio.
Afiliação
  • Mozzanica F; Department of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy. francesco.mozzanica@gmail.com.
  • Ferrulli A; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. francesco.mozzanica@gmail.com.
  • Vujosevic S; Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS Multimedica, Milan, Italy.
  • Montuori A; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
  • Cardella A; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
  • Preti A; Eye Clinic, IRCCS MultiMedica, Milan, Italy.
  • Ambrogi F; Department of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy.
  • Schindler A; Department of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy.
  • Terruzzi I; Department of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy.
  • Ottaviani F; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
  • Luzi L; Department of Biomedical and Clinical sciences "L. Sacco", Luigi Sacco University Hospital, University of Milan, Milan, Italy.
Endocrine ; 75(3): 760-767, 2022 Mar.
Article em En | MEDLINE | ID: mdl-34628556
PURPOSE: Scarce information on the prevalence and characteristics of olfactory disfunction (OD) in type 2 diabetic (T2D) patients are available. The aims of this study were (1) to assess the olfactory function in T2D patients and to compare it with a control group of individuals without T2D, and (2) to evaluate the differences in OD within T2D patients according to the presence of diabetic complications. METHODS: A group of 39 T2D patients and a control group of 39 healthy individuals were enrolled. Each subject underwent an evaluation of the olfactory performance using the Sniffing Olfactory Screening Test (SOST) and completed a questionnaire assessing the subjective perception of olfaction. According to the presence of diabetic complications, the group of T2D patients was divided into two subgroups. Non-parametric tests and regression analysis were used for statistical analysis. RESULTS: No differences in the subjective perception of olfaction were demonstrated among T2D patients (with and without complications) and controls. A significant difference for the SOST score was demonstrated among the different groups. In particular, OD was more frequent in T2D patients than in controls. In addition, OD was far more frequent in T2D patients with complications. Regression analysis did not demonstrate any significant association between OD and clinical/demographic characteristics of T2D patients. CONCLUSION: T2D patients were more frequently affected by OD. The subgroup analysis suggested a possible relationship between OD and diabetic complications since patients with T2D diabetic complications demonstrated lower olfactory abilities than controls subjects and T2D patients without diabetic complications.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações do Diabetes / Diabetes Mellitus Tipo 2 / Transtornos do Olfato Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Endocrine Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações do Diabetes / Diabetes Mellitus Tipo 2 / Transtornos do Olfato Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Endocrine Ano de publicação: 2022 Tipo de documento: Article