Non-cytochrome P450 enzymes involved in the oxidative metabolism of xenobiotics: Focus on the regulation of gene expression and enzyme activity.

Pang, Xiaoyan; Tang, Chongzhuang; Guo, Runcong; Chen, Xiaoyan

Pang, Xiaoyan; Tang, Chongzhuang; Guo, Runcong; Chen, Xiaoyan.

Afiliação

Pang X; Centre for Drug Metabolism and Pharmacokinetics Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, People's Republic of China.
Tang C; Centre for Drug Metabolism and Pharmacokinetics Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, People's Republic of China.
Guo R; Centre for Drug Metabolism and Pharmacokinetics Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, People's Republic of China.
Chen X; Centre for Drug Metabolism and Pharmacokinetics Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, People's Republic of China. Electronic address: xychen@simm.ac.cn.

Pharmacol Ther ; 233: 108020, 2022 05.

Article em En | MEDLINE | ID: mdl-34637840

Assuntos

Sistema Enzimático do Citocromo P-450; Xenobióticos; Aldeído Oxidase/metabolismo; Sistema Enzimático do Citocromo P-450/genética; Sistema Enzimático do Citocromo P-450/metabolismo; Regulação da Expressão Gênica; Humanos; Estresse Oxidativo; Xenobióticos/metabolismo

Palavras-chave

Inhibition; Non-CYP450 enzymes; Oxidative metabolism; Regulation; Species difference; Xenobiotics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xenobióticos / Sistema Enzimático do Citocromo P-450 Limite: Humans Idioma: En Revista: Pharmacol Ther Ano de publicação: 2022 Tipo de documento: Article

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