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Frontal and parietal background connectivity and their dynamic changes account for individual differences in the multisensory representation of peripersonal space.
Spadone, Sara; Perrucci, Mauro Gianni; Di Cosmo, Giulio; Costantini, Marcello; Della Penna, Stefania; Ferri, Francesca.
Afiliação
  • Spadone S; Department of Neuroscience, Imaging and Clinical Sciences - and ITAB, Institute for Advanced Biomedical Technologies, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy. s.spadone@unich.it.
  • Perrucci MG; Department of Neuroscience, Imaging and Clinical Sciences - and ITAB, Institute for Advanced Biomedical Technologies, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.
  • Di Cosmo G; Department of Neuroscience, Imaging and Clinical Sciences - and ITAB, Institute for Advanced Biomedical Technologies, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.
  • Costantini M; Department of Psychological, Health and Territorial Sciences - and ITAB, Institute for Advanced Biomedical Technologies, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.
  • Della Penna S; Department of Neuroscience, Imaging and Clinical Sciences - and ITAB, Institute for Advanced Biomedical Technologies, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.
  • Ferri F; Department of Neuroscience, Imaging and Clinical Sciences - and ITAB, Institute for Advanced Biomedical Technologies, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.
Sci Rep ; 11(1): 20533, 2021 10 15.
Article em En | MEDLINE | ID: mdl-34654814
ABSTRACT
Functional connectivity (FC) of brain networks dynamically fluctuates during both rest and task execution. Individual differences in dynamic FC have been associated with several cognitive and behavioral traits. However, whether dynamic FC also contributes to sensorimotor representations guiding body-environment interactions, such as the representation of peripersonal space (PPS), is currently unknown. PPS is the space immediately surrounding the body and acts as a multisensory interface between the individual and the environment. We used an audio-tactile task with approaching sounds to map the individual PPS extension, and fMRI to estimate the background FC. Specifically, we analyzed FC values for each stimulus type (near and far space) and its across-trial variability. FC was evaluated between task-relevant nodes of two fronto-parietal networks (the Dorsal Attention Network, DAN, and the Fronto-Parietal Network, FPN) and a key PPS region in the premotor cortex (PM). PM was significantly connected to specific task-relevant nodes of the DAN and the FPN during the audio-tactile task, and FC was stronger while processing near space, as compared to far space. At the individual level, less PPS extension was associated with stronger premotor-parietal FC during processing of near space, while the across-trial variability of premotor-parietal and premotor-frontal FC was higher during the processing of far space. Notably, only across-trial FC variability captured the near-far modulation of space processing. Our findings indicate that PM connectivity with task-relevant frontal and parietal regions and its dynamic changes participate in the mechanisms that enable PPS representation, in agreement with the idea that neural variability plays a crucial role in plastic and dynamic sensorimotor representations.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lobo Parietal / Espaço Pessoal / Percepção Espacial / Lobo Frontal Limite: Adult / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lobo Parietal / Espaço Pessoal / Percepção Espacial / Lobo Frontal Limite: Adult / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article