Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase.

Zhou, Yunzhuo; Portelli, Stephanie; Pat, Megan; Rodrigues, Carlos H M; Nguyen, Thanh-Binh; Pires, Douglas E V; Ascher, David B

Zhou, Yunzhuo; Portelli, Stephanie; Pat, Megan; Rodrigues, Carlos H M; Nguyen, Thanh-Binh; Pires, Douglas E V; Ascher, David B.

Afiliação

Zhou Y; Systems and Computational Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia.
Portelli S; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Pat M; Systems and Computational Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia.
Rodrigues CHM; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Nguyen TB; Systems and Computational Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia.
Pires DEV; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Ascher DB; Systems and Computational Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia.

Comput Struct Biotechnol J ; 19: 5381-5391, 2021.

Article em En | MEDLINE | ID: mdl-34667533

Palavras-chave

Abelson 1 kinase; Drug resistance; Graph-based signatures; Mutations; Structure-guided machine learning

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Comput Struct Biotechnol J Ano de publicação: 2021 Tipo de documento: Article

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