Electrolyte and renal disorders in patients with newly diagnosed glioblastoma.
Future Oncol
; 17(34): 4711-4719, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-34672208
ABSTRACT
Purpose:
Disturbances of electrolytes and renal function have been linked to the prognosis of critically ill patients and recently also of cancer patients. This study aimed to assess electrolyte and renal disorders in glioblastoma patients and evaluate their prognostic effect.Methods:
Medical records of patients with newly diagnosed glioblastoma between 2005 and 2018 were retrospectively reviewed for electrolyte and renal function parameters and for demographic, clinical and outcome parameters.Results:
Electrolyte and renal function disorders were associated with poorer survival in univariate and Kaplan-Meier analysis. Multivariate analysis revealed hypochloremia as an independent prognostic factor for overall and 1-year survival.Conclusion:
Only hypochloremia showed an association with glioblastoma prognosis, independent of other known prognostic factors, as age or molecular status.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Desequilíbrio Hidroeletrolítico
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Neoplasias Encefálicas
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Glioblastoma
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Insuficiência Renal
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Future Oncol
Ano de publicação:
2021
Tipo de documento:
Article