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The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms.
Korolev, Dmitry; Postnov, Viktor; Aleksandrov, Ilia; Murin, Igor.
Afiliação
  • Korolev D; Almazov National Medical Research Centre, Institute of Experimental Medicine, 2 Akkuratova Str., 197341 Saint Petersburg, Russia.
  • Postnov V; Almazov National Medical Research Centre, Institute of Experimental Medicine, 2 Akkuratova Str., 197341 Saint Petersburg, Russia.
  • Aleksandrov I; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Emb., 199034 Saint Petersburg, Russia.
  • Murin I; Almazov National Medical Research Centre, Institute of Experimental Medicine, 2 Akkuratova Str., 197341 Saint Petersburg, Russia.
Biomolecules ; 11(10)2021 10 19.
Article em En | MEDLINE | ID: mdl-34680176
This review presents the main patterns of synthesis for theranostics platforms. We examine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of nanoparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / Medicina de Precisão / Nanomedicina Teranóstica / Neoplasias Tipo de estudo: Screening_studies Limite: Humans Idioma: En Revista: Biomolecules Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / Medicina de Precisão / Nanomedicina Teranóstica / Neoplasias Tipo de estudo: Screening_studies Limite: Humans Idioma: En Revista: Biomolecules Ano de publicação: 2021 Tipo de documento: Article