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Association between Severity of Diffuse Idiopathic Skeletal Hyperostosis and Ossification of Other Spinal Ligaments in Patients with Ossification of the Posterior Longitudinal Ligament.
Nishimura, Soraya; Hirai, Takashi; Nagoshi, Narihito; Yoshii, Toshitaka; Hashimoto, Jun; Mori, Kanji; Maki, Satoshi; Katsumi, Keiichi; Takeuchi, Kazuhiro; Ushio, Shuta; Furuya, Takeo; Watanabe, Kei; Nishida, Norihiro; Kaito, Takashi; Kato, Satoshi; Nagashima, Katsuya; Koda, Masao; Nakashima, Hiroaki; Imagama, Shiro; Murata, Kazuma; Matsuoka, Yuji; Wada, Kanichiro; Kimura, Atsushi; Ohba, Tetsuro; Katoh, Hiroyuki; Watanabe, Masahiko; Matsuyama, Yukihiro; Ozawa, Hiroshi; Haro, Hirotaka; Takeshita, Katsushi; Matsukura, Yu; Inose, Hiroyuki; Yamazaki, Masashi; Watanabe, Kota; Matsumoto, Morio; Nakamura, Masaya; Okawa, Atsushi; Kawaguchi, Yoshiharu.
Afiliação
  • Nishimura S; Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Hirai T; Department of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.
  • Nagoshi N; Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Yoshii T; Department of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.
  • Hashimoto J; Department of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.
  • Mori K; Department of Orthopaedic Surgery, Shiga University of Medical Science, Otsu 520-2192, Japan.
  • Maki S; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba-shi 260-0856, Japan.
  • Katsumi K; Department of Orthopedic Surgery, Niigata University Medical and Dental General Hospital, Niigata-shi 951-8520, Japan.
  • Takeuchi K; Department of Orthopedic Surgery, National Hospital Organization Okayama Medical Center, Okayama-shi 701-1192, Japan.
  • Ushio S; Department of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.
  • Furuya T; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba-shi 260-0856, Japan.
  • Watanabe K; Department of Orthopedic Surgery, Niigata University Medical and Dental General Hospital, Niigata-shi 951-8520, Japan.
  • Nishida N; Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
  • Kaito T; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita 565-0871, Japan.
  • Kato S; Department of Orthopedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-8641, Japan.
  • Nagashima K; Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8577, Japan.
  • Koda M; Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8577, Japan.
  • Nakashima H; Department of Orthopaedics, Nagoya University Graduate School of Medicine, 65 Tsurumai, Shouwa-ku, Nagoya 464-8601, Japan.
  • Imagama S; Department of Orthopaedics, Nagoya University Graduate School of Medicine, 65 Tsurumai, Shouwa-ku, Nagoya 464-8601, Japan.
  • Murata K; Department of Orthopedic Surgery, Tokyo Medical University, Shinjuku, Tokyo 160-8402, Japan.
  • Matsuoka Y; Department of Orthopedic Surgery, Tokyo Medical University, Shinjuku, Tokyo 160-8402, Japan.
  • Wada K; Department of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
  • Kimura A; Department of Orthopedics, Jichi Medical University, Shimotsuke 329-0498, Japan.
  • Ohba T; Department of Orthopedic Surgery, University of Yamanashi, Chuo 409-3898, Japan.
  • Katoh H; Department of Orthopedic Surgery, Surgical Science, Tokai University School of Medicine, Isehara 259-1193, Japan.
  • Watanabe M; Department of Orthopedic Surgery, Surgical Science, Tokai University School of Medicine, Isehara 259-1193, Japan.
  • Matsuyama Y; Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu 431-3125, Japan.
  • Ozawa H; Department of Orthopaedic Surgery, Tohoku Medical and Pharmaceutical University, Sendai 981-8558, Japan.
  • Haro H; Department of Orthopedic Surgery, University of Yamanashi, Chuo 409-3898, Japan.
  • Takeshita K; Department of Orthopedics, Jichi Medical University, Shimotsuke 329-0498, Japan.
  • Matsukura Y; Department of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.
  • Inose H; Department of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.
  • Yamazaki M; Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8577, Japan.
  • Watanabe K; Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Matsumoto M; Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Nakamura M; Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Okawa A; Department of Orthopedic Surgery, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.
  • Kawaguchi Y; Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, Toyama-shi 930-0194, Japan.
J Clin Med ; 10(20)2021 Oct 13.
Article em En | MEDLINE | ID: mdl-34682814
BACKGROUND: Although diffuse idiopathic skeletal hyperostosis (DISH) is known to coexist with the ossification of spinal ligaments (OSLs), details of the radiographic relationship remain unclear. METHODS: We prospectively collected data of 239 patients with symptomatic cervical ossification of the posterior longitudinal ligament (OPLL) and analyzed the DISH severity on whole-spine computed tomography images, using the following grades: grade 0, no DISH; grade 1, DISH at T3-T10; grade 2, DISH at both T3-T10 and C6-T2 and/or T11-L2; and grade 3, DISH beyond C5 and/or L3. Ossification indices were calculated as the sum of vertebral and intervertebral levels with OSL for each patient. RESULTS: DISH was found in 107 patients (44.8%), 65 (60.7%) of whom had grade 2 DISH. We found significant associations of DISH grade with the indices for cervical OPLL (r = 0.45, p < 0.0001), thoracic ossification of the ligamentum flavum (OLF; r = 0.41, p < 0.0001) and thoracic ossification of the supra/interspinous ligaments (OSIL; r = 0.53, p < 0.0001). DISH grade was also correlated with the index for each OSL in the whole spine (OPLL: r = 0.29, p < 0.0001; OLF: r = 0.40, p < 0.0001; OSIL: r = 0.50, p < 0.0001). CONCLUSION: The DISH grade correlated with the indices of OSL at each high-prevalence level as well as the whole spine.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: J Clin Med Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: J Clin Med Ano de publicação: 2021 Tipo de documento: Article