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The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1.
Walter, Jonas; Bolognin, Silvia; Poovathingal, Suresh K; Magni, Stefano; Gérard, Deborah; Antony, Paul M A; Nickels, Sarah L; Salamanca, Luis; Berger, Emanuel; Smits, Lisa M; Grzyb, Kamil; Perfeito, Rita; Hoel, Fredrik; Qing, Xiaobing; Ohnmacht, Jochen; Bertacchi, Michele; Jarazo, Javier; Ignac, Tomasz; Monzel, Anna S; Gonzalez-Cano, Laura; Krüger, Rejko; Sauter, Thomas; Studer, Michèle; de Almeida, Luis Pereira; Tronstad, Karl J; Sinkkonen, Lasse; Skupin, Alexander; Schwamborn, Jens C.
Afiliação
  • Walter J; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Bolognin S; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Poovathingal SK; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Magni S; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Gérard D; Department of Life Science and Medicine (DLSM), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Antony PMA; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Nickels SL; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg; Department of Life Science and Medicine (DLSM), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Salamanca L; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Berger E; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Smits LM; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Grzyb K; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Perfeito R; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Rua Larga, Coimbra 3004-504, Portugal.
  • Hoel F; Department of Biomedicine, University of Bergen, Jonas Lies Vei 91, 5009 Bergen, Norway.
  • Qing X; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Ohnmacht J; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg; Department of Life Science and Medicine (DLSM), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Bertacchi M; Université Côte d'Azur, CNRS, Inserm, 06108 Nice, France.
  • Jarazo J; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Ignac T; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Monzel AS; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Gonzalez-Cano L; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Krüger R; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg; Transversal Translational Medicine, Luxembourg Institute of Health, Strassen, Luxembourg; Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg.
  • Sauter T; Department of Life Science and Medicine (DLSM), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Studer M; Université Côte d'Azur, CNRS, Inserm, 06108 Nice, France.
  • de Almeida LP; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Rua Larga, Coimbra 3004-504, Portugal; Faculty of Pharmacy, University of Coimbra, Coimbra 3000-548, Portugal.
  • Tronstad KJ; Department of Biomedicine, University of Bergen, Jonas Lies Vei 91, 5009 Bergen, Norway.
  • Sinkkonen L; Department of Life Science and Medicine (DLSM), University of Luxembourg, 4362 Belvaux, Luxembourg.
  • Skupin A; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg; Center for Research of Biological Systems, University of California, San Diego, La Jolla, CA 92093, USA.
  • Schwamborn JC; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Belvaux, Luxembourg. Electronic address: jens.schwamborn@uni.lu.
Cell Rep ; 37(3): 109864, 2021 10 19.
Article em En | MEDLINE | ID: mdl-34686322
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Encéfalo / Fator I de Transcrição COUP / Neurogênese / Células-Tronco Pluripotentes Induzidas / Células-Tronco Neurais / Neurônios Dopaminérgicos / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Encéfalo / Fator I de Transcrição COUP / Neurogênese / Células-Tronco Pluripotentes Induzidas / Células-Tronco Neurais / Neurônios Dopaminérgicos / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2021 Tipo de documento: Article