Easy synthesis of imidazo[1,5-a]indol-3-ones through Rh(III)-catalyzed C-H allenylation/annulation.
Chem Commun (Camb)
; 57(90): 12012-12015, 2021 Nov 11.
Article
em En
| MEDLINE
| ID: mdl-34710203
ABSTRACT
A highly efficient and regioselective synthesis of imidazo[1,5-a]indol-3-ones has been developed via a sequential C-H allenylation/annulation starting from easily available N-methoxycarbamoyl indoles and propargyl alcohols, in which the propargyl alcohols served as a C1 synthon. This strategy displays excellent regioselectivity, high atom economy and tolerates a broad substrate scope.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Chem Commun (Camb)
Ano de publicação:
2021
Tipo de documento:
Article