Profiling of ob/ob mice skeletal muscle exosome-like vesicles demonstrates combined action of miRNAs, proteins and lipids to modulate lipid homeostasis in recipient cells.

Jalabert, Audrey; Reininger, Laura; Berger, Emmanuelle; Coute, Yohann; Meugnier, Emmanuelle; Forterre, Alexis; Errazuriz-Cerda, Elizabeth; Geloen, Alain; Aouadi, Myriam; Bouzakri, Karim; Rieusset, Jennifer; Rome, Sophie

Jalabert, Audrey; Reininger, Laura; Berger, Emmanuelle; Coute, Yohann; Meugnier, Emmanuelle; Forterre, Alexis; Errazuriz-Cerda, Elizabeth; Geloen, Alain; Aouadi, Myriam; Bouzakri, Karim; Rieusset, Jennifer; Rome, Sophie.

Afiliação

Jalabert A; CarMeN Laboratory (INSERM 1060, INRAE 1397, INSA), Lyon-Sud Faculty of Medicine, University of Lyon, Oullins, France.
Reininger L; UMR DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Strasbourg, France.
Berger E; CarMeN Laboratory (INSERM 1060, INRAE 1397, INSA), Lyon-Sud Faculty of Medicine, University of Lyon, Oullins, France.
Coute Y; UMR Ecologie Microbienne Lyon (LEM), CNRS 5557, INRAE 1418, University of Lyon, VetAgro Sup, Villeurbanne, France.
Meugnier E; Univ. Grenoble-Alpes, Inserm, CEA, UMR BioSanté U1292, CNRS CEA FR2048, Grenoble, France.
Forterre A; CarMeN Laboratory (INSERM 1060, INRAE 1397, INSA), Lyon-Sud Faculty of Medicine, University of Lyon, Oullins, France.
Errazuriz-Cerda E; CarMeN Laboratory (INSERM 1060, INRAE 1397, INSA), Lyon-Sud Faculty of Medicine, University of Lyon, Oullins, France.
Geloen A; UMR DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Strasbourg, France.
Aouadi M; CIQLE, Claude Bernard Lyon 1 University, Lyon, France.
Bouzakri K; CarMeN Laboratory (INSERM 1060, INRAE 1397, INSA), Lyon-Sud Faculty of Medicine, University of Lyon, Oullins, France.
Rieusset J; UMR Ecologie Microbienne Lyon (LEM), CNRS 5557, INRAE 1418, University of Lyon, VetAgro Sup, Villeurbanne, France.
Rome S; Centre for Infectious Medicine, Department of Medicine, Karolinska Institutet, Huddinge, Sweden.

Sci Rep ; 11(1): 21626, 2021 11 03.

Article em En | MEDLINE | ID: mdl-34732797

Assuntos

Homeostase; Resistência à Insulina; Lipídeos/análise; MicroRNAs/genética; Proteínas Musculares/metabolismo; Músculo Esquelético/metabolismo; Atrofia Muscular/patologia; Tecido Adiposo; Animais; Exossomos/genética; Exossomos/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Obesos; Proteínas Musculares/genética; Atrofia Muscular/genética; Atrofia Muscular/metabolismo; Proteoma/análise; Proteoma/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Atrofia Muscular / Músculo Esquelético / MicroRNAs / Homeostase / Lipídeos / Proteínas Musculares Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article

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