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GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions.
Brun, Sonia; Bestion, Eloïne; Raymond, Eric; Bassissi, Firas; Jilkova, Zuzana Macek; Mezouar, Soraya; Rachid, Madani; Novello, Marie; Tracz, Jennifer; Hamaï, Ahmed; Lalmanach, Gilles; Vanderlynden, Lise; Legouffe, Raphael; Stauber, Jonathan; Schubert, Thomas; Plach, Maximilian G; Courcambeck, Jérôme; Drouot, Cyrille; Jacquemot, Guillaume; Serdjebi, Cindy; Roth, Gael; Baudoin, Jean-Pierre; Ansaldi, Christelle; Decaens, Thomas; Halfon, Philippe.
Afiliação
  • Brun S; Genoscience Pharma, Marseille, France.
  • Bestion E; Genoscience Pharma, Marseille, France.
  • Raymond E; Aix-Marseille Univ, MEPHI, APHM, IRD, IHU Méditerranée Infection, Marseille, France.
  • Bassissi F; Genoscience Pharma, Marseille, France.
  • Jilkova ZM; Medical Oncology, Paris Saint-Joseph Hospital, Paris, France.
  • Mezouar S; Genoscience Pharma, Marseille, France.
  • Rachid M; Institute for Advanced Biosciences, Research Center UGA/Inserm U 1209/CNRS 5309, La Tronche, France.
  • Novello M; University of Grenoble Alpes, Faculté De Médecine, France.
  • Tracz J; Clinique Universitaire d'Hépato-gastroentérologie, Pôle Digidune, Chu Grenoble, France.
  • Hamaï A; Genoscience Pharma, Marseille, France.
  • Lalmanach G; Genoscience Pharma, Marseille, France.
  • Vanderlynden L; Genoscience Pharma, Marseille, France.
  • Legouffe R; Genoscience Pharma, Marseille, France.
  • Stauber J; Institut Necker-Enfants Malades, Inserm U1151-CNRS UMR, Paris, France.
  • Schubert T; University of Paris Descartes-Sorbonne Paris Cité, Paris, France.
  • Plach MG; Inserm, UMR1100, Centre d'Etude Des Pathologies Respiratoires, Equipe "Mécanismes Protéolytiques Dans l'Inflammation", Tours, France.
  • Courcambeck J; University of Tours, Tours, France.
  • Drouot C; Inserm, UMR1100, Centre d'Etude Des Pathologies Respiratoires, Equipe "Mécanismes Protéolytiques Dans l'Inflammation", Tours, France.
  • Jacquemot G; University of Tours, Tours, France.
  • Serdjebi C; ImaBiotech, Loos, France.
  • Roth G; ImaBiotech, Billerica, USA.
  • Baudoin JP; 2Bind GmbH, Regensburg, Germany.
  • Ansaldi C; 2Bind GmbH, Regensburg, Germany.
  • Decaens T; Genoscience Pharma, Marseille, France.
  • Halfon P; Genoscience Pharma, Marseille, France.
Autophagy ; 18(3): 678-694, 2022 03.
Article em En | MEDLINE | ID: mdl-34740311
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas / Antineoplásicos Limite: Humans Idioma: En Revista: Autophagy Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas / Antineoplásicos Limite: Humans Idioma: En Revista: Autophagy Ano de publicação: 2022 Tipo de documento: Article