C1q and SRPX2 regulate microglia mediated synapse elimination during early development in the visual thalamus but not the visual cortex.

Cong, Qifei; Soteros, Breeanne M; Huo, Anran; Li, Yang; Tenner, Andrea J; Sia, Gek Ming

Cong, Qifei; Soteros, Breeanne M; Huo, Anran; Li, Yang; Tenner, Andrea J; Sia, Gek Ming.

Afiliação

Cong Q; Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Soteros BM; Institutes of Neuroscience, Soochow University, Suzhou, China.
Huo A; Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Li Y; Institutes of Neuroscience, Soochow University, Suzhou, China.
Tenner AJ; Department of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Sia GM; Department of Molecular Biology and Biochemistry, University of California, Irvine, California, USA.

Glia ; 70(3): 451-465, 2022 03.

Article em En | MEDLINE | ID: mdl-34762332

Assuntos

Proteínas de Membrana/metabolismo; Microglia; Proteínas de Neoplasias/metabolismo; Córtex Visual; Animais; Complemento C1q/genética; Complemento C1q/metabolismo; Camundongos; Microglia/metabolismo; Sinapses/metabolismo; Tálamo/metabolismo; Córtex Visual/metabolismo

Palavras-chave

complement; microglia engulfment; synapse elimination; visual system

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Visual / Microglia / Proteínas de Membrana / Proteínas de Neoplasias Limite: Animals Idioma: En Revista: Glia Ano de publicação: 2022 Tipo de documento: Article

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