Clinical HDAC Inhibitors Are Effective Drugs to Prevent the Entry of SARS-CoV2.
ACS Pharmacol Transl Sci
; 3(6): 1361-1370, 2020 Dec 11.
Article
em En
| MEDLINE
| ID: mdl-34778724
ABSTRACT
The outbreak of COVID-19 by the end of 2019 has posed serious health threats to humanity and jeopardized the global economy. However, no effective drugs are available to treat COVID-19 currently and there is a great demand to fight against it. Here, we combined computational screening and an efficient cellular pseudotyped virus system, confirming that clinical HDAC inhibitors can efficiently prevent SARS-CoV-2 and potentially be used to fight against COVID-19.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
ACS Pharmacol Transl Sci
Ano de publicação:
2020
Tipo de documento:
Article