Results of Complex Immunopharmacological Analysis of the Mechanisms of Action of Bioregulation Agents.

Kazimirskii, Ð N; Salmasi, Z Ð; Poryadin, G V; Kukes, I V

Kazimirskii, Ð N; Salmasi, Z Ð; Poryadin, G V; Kukes, I V.

Afiliação

Kazimirskii ÐN; N. I. Pirogov Russian National Research Medical University, Ministry of the Health of the Russian Federation, Moscow, Russia. alnica10@mail.ru.
Salmasi ZÐ; N. I. Pirogov Russian National Research Medical University, Ministry of the Health of the Russian Federation, Moscow, Russia.
Poryadin GV; N. I. Pirogov Russian National Research Medical University, Ministry of the Health of the Russian Federation, Moscow, Russia.
Kukes IV; Scientific and Clinical Department, ANO "International Association of Clinical Pharmacologists and Pharmacists", Moscow, Russia.

Bull Exp Biol Med ; 172(1): 38-41, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34792717

RESUMO

Elucidation of the pharmacodynamic mechanisms of drugs capable of potentiating the effects of non-steroidal anti-inflammatory drugs is an important task. In this in vitro study, the ability of Traumeel S to influence the innate and acquired immunity was evaluated. Traumeel S was found to reduce activities of NADPH oxidase and neutrophil extracellular traps, as well as to evoke anti-inflammatory activity of lymphocyte subpopulations.

Assuntos

Anti-Inflamatórios não Esteroides/farmacologia; Anti-Inflamatórios/farmacologia; Armadilhas Extracelulares/imunologia; Minerais/farmacologia; NADPH Oxidases/metabolismo; Extratos Vegetais/farmacologia; Imunidade Adaptativa/efeitos dos fármacos; Antígenos HLA-DR/imunologia; Humanos; Imunidade Inata/efeitos dos fármacos; Inflamação/tratamento farmacológico; Inflamação/patologia; Leucocitose/imunologia; Subpopulações de Linfócitos/imunologia; Neutrófilos/imunologia; Linfócitos T/imunologia; Receptor fas/análise

Palavras-chave

Traumeel S; inflammation; lymphocytes; neutrophil extracellular traps; nonsteroidal anti-inflammatory drugs

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Anti-Inflamatórios não Esteroides / NADPH Oxidases / Armadilhas Extracelulares / Anti-Inflamatórios / Minerais Limite: Humans Idioma: En Revista: Bull Exp Biol Med Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google