Sweet sensation: Developing a single-cell fluorescent reporter of glycolytic heterogeneity.

Karloff, Diane B; Heemstra, Jennifer M

Karloff, Diane B; Heemstra, Jennifer M.

Afiliação

Karloff DB; Department of Chemistry, Emory University, Atlanta, GA 30322, USA.
Heemstra JM; Department of Chemistry, Emory University, Atlanta, GA 30322, USA; Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA. Electronic address: jen.heemstra@emory.edu.

Cell Chem Biol ; 28(11): 1539-1541, 2021 11 18.

Article em En | MEDLINE | ID: mdl-34798034

ABSTRACT

ABSTRACT

Conversion of in vitro selected aptamers into functional metabolic sensors is hampered by reduced in vivo aptamer binding and limited tunability of cellular metabolite levels. In this issue of Cell Chemical Biology, Ortega et al. (2021) construct RNA sensors of fructose-6-bisphosphate (FBP) that report on metabolite levels within single yeast cells.

Assuntos

Frutosedifosfatos; Glicólise; Corantes; RNA; Sensação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Frutosedifosfatos / Glicólise Idioma: En Revista: Cell Chem Biol Ano de publicação: 2021 Tipo de documento: Article

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