Cholesterol-Based Nanovesicles Enhance the In Vitro Cytotoxicity, Ex Vivo Intestinal Absorption, and In Vivo Bioavailability of Flutamide.

Ali, Mohamed A; Mohamed, Magdy I; Megahed, Mohamed A; Abdelghany, Tamer M; El-Say, Khalid M

Ali, Mohamed A; Mohamed, Magdy I; Megahed, Mohamed A; Abdelghany, Tamer M; El-Say, Khalid M.

Afiliação

Ali MA; Department of Pharmaceutics and Pharmaceutical Technology, Egyptian Russian University, Cairo 11829, Egypt.
Mohamed MI; Department of Pharmaceutics and Industrial Pharmacy, Cairo University, Cairo 11562, Egypt.
Megahed MA; Department of Pharmaceutics and Pharmaceutical Technology, Egyptian Russian University, Cairo 11829, Egypt.
Abdelghany TM; Department of Pharmacology and Toxicology, Al-Azhar University, Cairo 11651, Egypt.
El-Say KM; Department of Pharmacology and Toxicology, Heliopolis University for Sustainable Development, Cairo 11785, Egypt.

Pharmaceutics ; 13(11)2021 Oct 20.

Article em En | MEDLINE | ID: mdl-34834155

Palavras-chave

DraperLin small composite design; ex vivo intestinal permeation; flutamide; in vitro cytotoxicity; in vivo pharmacokinetics; optimization; prostate cancer

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2021 Tipo de documento: Article