The vaccination threshold for SARS-CoV-2 depends on the indoor setting and room ventilation.
BMC Infect Dis
; 21(1): 1193, 2021 Nov 26.
Article
em En
| MEDLINE
| ID: mdl-34836502
ABSTRACT
BACKGROUND:
Effective vaccines are now available for SARS-CoV-2 in the 2nd year of the COVID-19 pandemic, but there remains significant uncertainty surrounding the necessary vaccination rate to safely lift occupancy controls in public buildings and return to pre-pandemic norms. The aim of this paper is to estimate setting-specific vaccination thresholds for SARS-CoV-2 to prevent sustained community transmission using classical principles of airborne contagion modeling. We calculated the airborne infection risk in three settings, a classroom, prison cell block, and restaurant, at typical ventilation rates, and then the expected number of infections resulting from this risk at varying percentages of occupant immunity.RESULTS:
We estimate the setting-specific immunity threshold for control of wild-type SARS-CoV-2 to range from a low of 40% for a mechanically ventilation classroom to a high of 85% for a naturally ventilated restaurant.CONCLUSIONS:
If vaccination rates are limited to a theoretical minimum of approximately two-thirds of the population, enhanced ventilation above minimum standards for acceptable air quality is needed to reduce the frequency and severity of SARS-CoV-2 superspreading events in high-risk indoor environments.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
/
4_TD
Base de dados:
MEDLINE
Assunto principal:
Poluição do Ar em Ambientes Fechados
/
COVID-19
Limite:
Humans
Idioma:
En
Revista:
BMC Infect Dis
Ano de publicação:
2021
Tipo de documento:
Article