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Pharmacokinetic and pharmacogenomic analysis of low-dose afatinib treatment in elderly patients with EGFR mutation-positive non-small cell lung cancer.
Mizugaki, Hidenori; Oizumi, Satoshi; Fujita, Yuka; Harada, Toshiyuki; Nakahara, Yoshiro; Takashina, Taichi; Ko, Ryo; Watanabe, Kageaki; Hotta, Takamasa; Minemura, Hiroyuki; Saeki, Sho; Asahina, Hajime; Nakamura, Keiichi; Nakamura, Hiromi; Hosoda, Fumie; Yagishita, Shigehiro; Hamada, Akinobu.
Afiliação
  • Mizugaki H; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, Sapporo, Japan. Electronic address: hidenori.mizugaki@jfcr.or.jp.
  • Oizumi S; Department of Respiratory Medicine, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan.
  • Fujita Y; Department of Respiratory Medicine, National Hospital Organization Asahikawa Medical Center, Asahikawa, Japan.
  • Harada T; Department of Respiratory Medicine, Japan Community Health Care Organization Hokkaido Hospital, Sapporo, Japan.
  • Nakahara Y; Department of Respiratory Medicine, Kitasato University School of Medicine, Kanagawa, Japan.
  • Takashina T; Division of Respiratory Medicine, Iwamizawa Municipal General Hospital, Iwamizawa, Japan.
  • Ko R; Department of Respiratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
  • Watanabe K; Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
  • Hotta T; Division of Medical Oncology and Respiratory Medicine, Department of Internal Medicine, Shimane University, School of Medicine, Shimane, Japan.
  • Minemura H; Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan.
  • Saeki S; Department of Respiratory Medicine, Kumamoto University Hospital, Kumamoto, Japan.
  • Asahina H; Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, Sapporo, Japan.
  • Nakamura K; Department of Respiratory Medicine, National Hospital Organization Asahikawa Medical Center, Asahikawa, Japan.
  • Nakamura H; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
  • Hosoda F; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
  • Yagishita S; Division of Molecular Pharmacology, National Cancer Center Research Institute, Tokyo, Japan.
  • Hamada A; Division of Molecular Pharmacology, National Cancer Center Research Institute, Tokyo, Japan.
Eur J Cancer ; 160: 227-234, 2022 01.
Article em En | MEDLINE | ID: mdl-34862083
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Inibidores de Proteínas Quinases / Afatinib / Neoplasias Pulmonares Aspecto: Patient_preference Limite: Aged / Female / Humans / Male Idioma: En Revista: Eur J Cancer Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Inibidores de Proteínas Quinases / Afatinib / Neoplasias Pulmonares Aspecto: Patient_preference Limite: Aged / Female / Humans / Male Idioma: En Revista: Eur J Cancer Ano de publicação: 2022 Tipo de documento: Article