Tricking enzymes in living cells: a mechanism-based strategy for design of DNA topoisomerase biosensors.

Ba, Sai; Gao, Guangpeng; Li, Tianhu; Zhang, Hao

Ba, Sai; Gao, Guangpeng; Li, Tianhu; Zhang, Hao.

Afiliação

Ba S; School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an, 710072, China.
Gao G; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, 637371, Singapore.
Li T; School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an, 710072, China.
Zhang H; School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an, 710072, China. tianhuli@nwpu.edu.cn.

J Nanobiotechnology ; 19(1): 407, 2021 Dec 07.

Article em En | MEDLINE | ID: mdl-34876137

Assuntos

Técnicas Biossensoriais/métodos; DNA Topoisomerases; Sondas Moleculares; Neoplasias; Sistema Livre de Células; Células Cultivadas; DNA/química; DNA/metabolismo; DNA Topoisomerases/análise; DNA Topoisomerases/química; DNA Topoisomerases/genética; DNA Topoisomerases/metabolismo; Humanos; Sondas Moleculares/química; Sondas Moleculares/metabolismo; Nanotecnologia; Neoplasias/diagnóstico; Neoplasias/metabolismo

Palavras-chave

Cancer diagnosis; DNA nanotechnology; DNA topoisomerases; Diagnostic probes; Enzyme mechanisms

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Sondas Moleculares / DNA Topoisomerases / Neoplasias Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: J Nanobiotechnology Ano de publicação: 2021 Tipo de documento: Article

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