Clinical translation of advanced colonic drug delivery technologies.

Awad, Atheer; Madla, Christine M; McCoubrey, Laura E; Ferraro, Fabiana; Gavins, Francesca K H; Buanz, Asma; Gaisford, Simon; Orlu, Mine; Siepmann, Florence; Siepmann, Juergen; Basit, Abdul W

Awad, Atheer; Madla, Christine M; McCoubrey, Laura E; Ferraro, Fabiana; Gavins, Francesca K H; Buanz, Asma; Gaisford, Simon; Orlu, Mine; Siepmann, Florence; Siepmann, Juergen; Basit, Abdul W.

Afiliação

Awad A; 29 - 39 Brunswick Square, UCL School of Pharmacy, University College London, London WC1N 1AX, United Kingdom.
Madla CM; 29 - 39 Brunswick Square, UCL School of Pharmacy, University College London, London WC1N 1AX, United Kingdom.
McCoubrey LE; 29 - 39 Brunswick Square, UCL School of Pharmacy, University College London, London WC1N 1AX, United Kingdom.
Ferraro F; Univ. Lille, Inserm, CHU Lille, U1008, F-59000 Lille, France.
Gavins FKH; 29 - 39 Brunswick Square, UCL School of Pharmacy, University College London, London WC1N 1AX, United Kingdom.
Buanz A; 29 - 39 Brunswick Square, UCL School of Pharmacy, University College London, London WC1N 1AX, United Kingdom.
Gaisford S; 29 - 39 Brunswick Square, UCL School of Pharmacy, University College London, London WC1N 1AX, United Kingdom.
Orlu M; 29 - 39 Brunswick Square, UCL School of Pharmacy, University College London, London WC1N 1AX, United Kingdom.
Siepmann F; Univ. Lille, Inserm, CHU Lille, U1008, F-59000 Lille, France.
Siepmann J; Univ. Lille, Inserm, CHU Lille, U1008, F-59000 Lille, France.
Basit AW; 29 - 39 Brunswick Square, UCL School of Pharmacy, University College London, London WC1N 1AX, United Kingdom. Electronic address: a.basit@ucl.ac.uk.

Adv Drug Deliv Rev ; 181: 114076, 2022 02.

Article em En | MEDLINE | ID: mdl-34890739

Assuntos

Colo/efeitos dos fármacos; Colo/fisiologia; Sistemas de Liberação de Medicamentos/métodos; Produtos Biológicos/administração & dosagem; Preparações de Ação Retardada; Microbioma Gastrointestinal/fisiologia; Trânsito Gastrointestinal/fisiologia; Humanos; Concentração de Íons de Hidrogênio; Síndrome do Intestino Irritável/tratamento farmacológico; Prebióticos/administração & dosagem; Impressão Tridimensional; Probióticos/administração & dosagem; Fatores de Tempo; Vacinas/administração & dosagem

Palavras-chave

3D printing drug products and medicines; ASACOL 1600; Chronotherapy and drug absorption; Colonic drug targeting; Drug delivery to the large intestine; Gastro resistant film coatings; Inflammatory bowel disease (ulcerative colitis and Crohn's disease); Mesalazine formulations; Phloral; Polysaccharides and fermentation

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 3_ND Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Colo Limite: Humans Idioma: En Revista: Adv Drug Deliv Rev Ano de publicação: 2022 Tipo de documento: Article

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