DNA methylation of <i>ARHGAP30</i> is negatively associated with <i>ARHGAP30</i> expression in lung adenocarcinoma, which reduces tumor immunity and is detrimental to patient survival.

Hu, Sheng; Zhang, Wenxiong; Ye, Jiayue; Zhang, Yang; Zhang, Deyuan; Peng, Jinhua; Yu, Dongliang; Xu, Jianjun; Wei, Yiping

DNA methylation of ARHGAP30 is negatively associated with ARHGAP30 expression in lung adenocarcinoma, which reduces tumor immunity and is detrimental to patient survival.

Hu, Sheng; Zhang, Wenxiong; Ye, Jiayue; Zhang, Yang; Zhang, Deyuan; Peng, Jinhua; Yu, Dongliang; Xu, Jianjun; Wei, Yiping.

Afiliação

Hu S; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zhang W; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Ye J; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zhang Y; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zhang D; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Peng J; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Yu D; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Xu J; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Wei Y; Department of Thoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.

Aging (Albany NY) ; 13(24): 25799-25845, 2021 12 15.

Article em En | MEDLINE | ID: mdl-34910688

Assuntos

Adenocarcinoma de Pulmão/genética; Metilação de DNA/genética; Proteínas Ativadoras de GTPase/genética; Neoplasias Pulmonares/genética; Linfócitos do Interstício Tumoral/patologia; Adenocarcinoma de Pulmão/mortalidade; Adenocarcinoma de Pulmão/patologia; Ontologia Genética; Humanos; Neoplasias Pulmonares/mortalidade; Neoplasias Pulmonares/patologia; Prognóstico

Palavras-chave

ARHGAP30; DNA methylation; gene set enrichment analysis (GSEA); lung adenocarcinoma; tumor immunity

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Linfócitos do Interstício Tumoral / Metilação de DNA / Proteínas Ativadoras de GTPase / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Aging (Albany NY) Ano de publicação: 2021 Tipo de documento: Article

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