[Stem cell therapy for erectile dysfunction: An update].
Zhonghua Nan Ke Xue
; 27(3): 256-261, 2021 Mar.
Article
em Zh
| MEDLINE
| ID: mdl-34914309
ABSTRACT
Erectile dysfunction (ED) is a common andrological disorder, and traditional oral drugs often fail to achieve satisfactory therapeutic effects. As a new field of biomedicine, stem cell therapy (SCT) has seen a significantly increasing number of researches on its treatment of ED in recent years. Preclinical animal models for the study of ED mainly include the models of diabetes mellitus-, aging-, cavernous nerve injury-, and Peyronie's disease-related ED. Previous studies indicated that SCT improved erectile function through paracrine and was more effective when combined with other therapies than used alone in restoring ED-induced pathological changes. Although clinical trials on SCT have partially proved its safety and effectiveness for the treatment of ED, they were still in the early stages and with relatively small sample sizes. This article summarizes the latest advances in the treatment of ED by SCT.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Induração Peniana
/
Disfunção Erétil
Limite:
Animals
/
Humans
/
Male
Idioma:
Zh
Revista:
Zhonghua Nan Ke Xue
Ano de publicação:
2021
Tipo de documento:
Article