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Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates.
Ghanim, Amany M; Girgis, Adel S; Kariuki, Benson M; Samir, Nermin; Said, Mona F; Abdelnaser, Anwar; Nasr, Soad; Bekheit, Mohamed S; Abdelhameed, Mohamed F; Almalki, Ahmad J; Ibrahim, Tarek S; Panda, Siva S.
Afiliação
  • Ghanim AM; Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, USA; Department of Pharmaceutical Organic Chemistry Faculty of Pharmacy, Zagazig University, 44519 Zagazig, Egypt.
  • Girgis AS; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt.
  • Kariuki BM; School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, UK.
  • Samir N; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.
  • Said MF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
  • Abdelnaser A; Institute of Global Health and Human Ecology, School of Sciences and Engineering, The American University in Cairo (AUC), Cairo 11835, Egypt.
  • Nasr S; Institute of Global Health and Human Ecology, School of Sciences and Engineering, The American University in Cairo (AUC), Cairo 11835, Egypt; Institute of Pharmacology of Natural Products & Clinical Pharmacology, Ulm University, D-89081 Ulm, Germany.
  • Bekheit MS; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt.
  • Abdelhameed MF; Pharmacology Department, National Research Centre, Dokki, Giza 12622, Egypt.
  • Almalki AJ; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Center of Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
  • Ibrahim TS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
  • Panda SS; Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, USA. Electronic address: sipanda@augusta.edu.
Bioorg Chem ; 119: 105557, 2022 02.
Article em En | MEDLINE | ID: mdl-34952242
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Desenho de Fármacos / Anti-Inflamatórios não Esteroides / Ibuprofeno / Inibidores de Ciclo-Oxigenase / Analgésicos Limite: Animals Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Desenho de Fármacos / Anti-Inflamatórios não Esteroides / Ibuprofeno / Inibidores de Ciclo-Oxigenase / Analgésicos Limite: Animals Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article